Fluorescence Correlation Spectroscopy Single Molecule Analyzer SX Series

The world's first desktop fluorescence correlation spectrometer, integrated all-in-one instrument, no need to use with a microscope, selected as the first batch of recommended domestic instrument catalog by the Chinese Academy of Sciences, and is a high-tech and famous product of Guangdong Province.

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Product description

Parameters

Versatile analysis of biomacromolecular and nanoparticle properties in solution samples or cell lysate:

Molecular interaction affinity and kinetic constants
Single molecule conformation and conformational conversion rate
Diffusion coefficient/hydrodynamic radius of the molecule or nanoparticle
Molarity of the molecule or nanoparticle

Examples of cutting-edge applications:

Liquid-liquid phase separation of biological macromolecules
Molecular interactions in cell biology and drug screening
Molecular dynamic structure-functional mechanisms
Photophysical properties of fluorescent probe molecules or nanoparticles
Denatured aggregation of biological macromolecules
Stability and metabolic analysis of nanodrugs in plasma

Product characteristics

Functional indicators

Linear range for measuring molecular or nanoparticle concentration: 10pM-100nM

Measure the hydrodynamic radius of molecules or nanoparticles: < 100 nm

Measure the dissociation constant of molecular binding (e.g., antigen-antibody) reactions K_D Measurement range: pM-μM

Single-molecule fluorescence signal analysis: Alternative Laser Excitation Single-molecule FRET (ALEXsmFRET); coincidence analysis, etc

Typical user

National Institutes of Health, Peking University

University of California, San Francisco Tsinghua University

Institute of Biophysics, Chinese Academy of Sciences, School of Medicine, University of Mach Province

AstraZeneca Pharmaceuticals Northwest Institute of Plateau Biology, Chinese Academy of Sciences

University of Macau, Institute of Oncology and Basic Medicine, Chinese Academy of Sciences

Model configuration

Model configuration table
●Standard ○Optional X Not optional ☆Customized
Model			SX100	SX200	SX300
function	Fluorescence autocorrelation analysis		●	●	●
	Fluorescence correlation analysis		○	●	●
	Single molecule fluorescence analysis		X	○	●
laser	Laser I.		●	●	●
	Laser II.		○	●	●
	Laser III.		○	○	●
	Alternately excited		X	○	●
detector	Detector I.		●	●	●
detector	Detector II		○	●	●
Optical system	Aqueous high digital aperture apochromatic microscope objectives		●	●	●
Optical system	Confocal pinhole automatic calibration system		●	●	●
Related compute cards	Hardware-dependent compute cards		●	●	●
Related compute cards	Single-photon timing signal output		X	○	●
Sample bin	Laser safety protection device		●	●	●
	Temperature detection		●	●	●
	Sample temperature control device		○	○	●
	Motorized sample stage		●	●	●
	Eight-well box sample cell		●	●	●
	Custom sample cells		☆	☆	☆
other	Microscope docking		X	X	X
3. Software	Data acquisition software		●	●	●
	Data analysis software		●	●	●
	Extend analytics capabilities	Interchange correlation analysis	○	●	●
		Single molecule fluorescence analysis	X	○	●
		Molecular interactions	●	●	●
		Particle size distribution	●	●	●
		Phase change analysis	X	○	○
		Drug screening	X	○	○
	Customize data analysis capabilities		☆	☆	☆

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Fluorescence Correlation Spectroscopy Single Molecule Analyzer CX Series

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