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Fluorescence Correlation Spectroscopy Single Molecule Analyzer SX Series
Versatile analysis of biomacromolecular and nanoparticle properties in solution samples or cell lysate:
- Molecular interaction affinity and kinetic constants
- Single molecule conformation and conformational conversion rate
- Diffusion coefficient/hydrodynamic radius of the molecule or nanoparticle
- Molarity of the molecule or nanoparticle
Examples of cutting-edge applications:
- Liquid-liquid phase separation of biological macromolecules
- Molecular interactions in cell biology and drug screening
- Molecular dynamic structure-functional mechanisms
- Photophysical properties of fluorescent probe molecules or nanoparticles
- Denatured aggregation of biological macromolecules
- Stability and metabolic analysis of nanodrugs in plasma
Product characteristics
Functional indicators
Linear range for measuring molecular or nanoparticle concentration: 10pM-100nM
Measure the hydrodynamic radius of molecules or nanoparticles: < 100 nm
Measure the dissociation constant of molecular binding (e.g., antigen-antibody) reactions KD Measurement range: pM-μM
Single-molecule fluorescence signal analysis: Alternative Laser Excitation Single-molecule FRET (ALEXsmFRET); coincidence analysis, etc
Typical user
National Institutes of Health, Peking University
University of California, San Francisco Tsinghua University
Institute of Biophysics, Chinese Academy of Sciences, School of Medicine, University of Mach Province
AstraZeneca Pharmaceuticals Northwest Institute of Plateau Biology, Chinese Academy of Sciences
University of Macau, Institute of Oncology and Basic Medicine, Chinese Academy of Sciences
Model configuration
Model configuration table |
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●Standard ○Optional X Not optional ☆Customized |
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Model |
SX100 |
SX200 |
SX300 |
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function |
Fluorescence autocorrelation analysis |
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Fluorescence correlation analysis |
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Single molecule fluorescence analysis |
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laser |
Laser I. |
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Laser II. |
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Laser III. |
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Alternately excited |
X |
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detector |
Detector I. |
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Detector II |
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Optical system |
Aqueous high digital aperture apochromatic microscope objectives |
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Confocal pinhole automatic calibration system |
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Related compute cards |
Hardware-dependent compute cards |
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Single-photon timing signal output |
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Sample bin |
Laser safety protection device |
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Temperature detection |
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Sample temperature control device |
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Motorized sample stage |
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Eight-well box sample cell |
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Custom sample cells |
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other |
Microscope docking |
X |
X |
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3. Software |
Data acquisition software |
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Data analysis software |
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Extend analytics capabilities |
Interchange correlation analysis |
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Single molecule fluorescence analysis |
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Molecular interactions |
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Particle size distribution |
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Phase change analysis |
X |
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Drug screening |
X |
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Customize data analysis capabilities |
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Related products
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Contact information
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Zhongke Aohui leads the industry with innovation and serves the society with science and technology

Company name: Guangdong Zhongke Aohui Technology Co., LTD
Company telephone:0760-88287898
Email:info@lightedgetech.com
Company Address: Floor 3, Building 2, Cuihai Dao East Sanwei GMP Workshop, Cuiheng New District, Zhongshan City, Guangdong Province
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