Combination of multiple microscope platforms
Combined with a wide field, confocal, total internal reflection, multiphoton, light sheet, STED superresolution microscope platform, the advantages of each fluorescence microscope imaging mode to integrate fluorescence spectroscopy with single molecule resolution function.
Linear range of measurement of molecular or nanoparticle concentration: 10pm-500nm
Measurement of molecular or nanoparticle hydrodynamic radius: <100nm
The dissociation constant KD, which measures molecular binding (e.g., antigen-antibody) reactions, is measured in the pM-μm range
Excitation Excitation is Alternative Laser Excitation single-molecule FRET(ALEXsmFRET). Coincidence analysis etc.
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